A The Simpsons question: Is Homer's crush Mindy Simmons the granddaughter of Abe Simpson's deceased girlfriend Bea Simmons??

That is a pretty wild theory, but honestly, I don't think there is any actual connection there. I have been watching the show since I was a kid, and the writers usually like to keep those kinds of relationships pretty separate unless they are making a specific joke about it. Bea Simmons was basically just a short-lived character to give Abe some development, while Mindy was just a one-off plot device to tempt Homer. It would be a funny little bit of lore if they were related, but it never really came up on screen.

If you look at how the show handles these things, they usually just reuse surnames because it is easier or they just don't think that deep into the family trees. You know how it is with cartoons, sometimes a name is just a name. It is fun to speculate, though, especially since the show has been running for so long that you start seeing patterns that probably aren't even there. I wouldn't bet on them being family, but hey, in the world of Springfield, anything is possible if the writers decide to make a joke out of it later.