​on which organ or tissue does leptin primarily act

Leptin primarily acts on adipose (fat) tissue in the body. It is a hormone produced by adipocytes (fat cells) and plays a crucial role in regulating energy balance and body weight. Leptin acts as a signal to the brain, particularly the hypothalamus, informing it about the body’s energy status. When leptin levels are high, it signals to the brain that the body has sufficient energy stores, which can lead to reduced appetite and increased energy expenditure. Conversely, low leptin levels can signal hunger and decreased energy expenditure, helping to maintain energy homeostasis in the body.